Megaloblastic anemia: Clinical spectrum and hematological profile

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Clinico-hematological profile of megaloblastic anemia.

Subject and Methods Twenty nine children (age range 3 months to 12 years) diagnosed as megaloblastic anemia over a period of three year (March 1993 to March 1996) were prospectively studied. All anemic children admitted with or without bleeding manifestations had their peripheral blood smear examined. Complete hemogram including platelet count and mean corpuscular volume (MCV) were also carried...

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LTHOUGH megaboblastic anemia of pregnancy is considered mainly as a folic acid deficiency anemia, since this vitamin induces remission in most cases, its mechanism of production is still obscure. Dietary deficiency has been claimed to be the principal cause. However, this anemia has been observed in well-to-do women whose diet was satisfactory. Some other factors such as gastrointestinal upset,...

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Megaloblastic Anemia in Pregnancy

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Drug-Induced Megaloblastic Anemia.

More than 50 years ago, Victor Herbert first described the concept that defective nucleoprotein synthesis, attributable to various causes, results in the development of megaloblastic anemia.1 Megaloblastic anemia is characterized by the presence of a hypercellular marrow with large, abnormal hematopoietic progenitor cells with a characteristic finely stippled, lacy nuclear chromatin pattern. Th...

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Megaloblastic anemia complicating thalassemia.

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ژورنال

عنوان ژورنال: Medical Journal of Dr. D.Y. Patil University

سال: 2016

ISSN: 0975-2870

DOI: 10.4103/0975-2870.194231